A headache cocktail iv may be prescribed to treat a headache. The iv includes a combination of medications that are administered through a vein.

The medications in a headache cocktail iv may include dihydroergotamine (DHE), prochlorperazine (Compazine), and diphenhydramine (Benadryl). DHE is a medication that helps to narrow the blood vessels in the head. Prochlorperazine is a medication that helps to decrease the inflammation around the blood vessels. Diphenhydramine is a medication that helps to decrease the sensitivity of the …